Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19623269 | 0.76 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL22612768 | 0.75 | RAF1 (0.43) | RAF1BRAF | |
| SCHEMBL20008343 | 0.69 | RAF1 (0.38) | RAF1BRAF | |
| SCHEMBL20008439 | 0.69 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL26165525 | 0.67 | RAB9A (0.60) | RAF1BRAF | |
| SCHEMBL30017068 | 0.66 | RAF1 (0.42) | RAF1BRAF | |
| SCHEMBL28632451 | 0.66 | RAF1 (0.42) | RAF1BRAF | |
| SCHEMBL20009217 | 0.66 | RAF1 (0.39) | RAF1BRAF | |
| SCHEMBL23654063 | 0.65 | RAF1 (0.43) | RAF1BRAF | |
| SCHEMBL21624459 | 0.64 | NPC1 (0.56) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |