Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21987011 | 0.66 | ALDH1A1 (0.50) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL21987080 | 0.66 | ALDH1A1 (0.50) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL22783869 | 0.65 | ALDH1A1 (0.49) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL10583065 | 0.65 | ALDH1A1 (0.49) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL10583061 | 0.65 | ALDH1A1 (0.49) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL2673508 | 0.64 | ALDH1A1 (0.47) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL456777 | 0.64 | ALDH1A1 (0.47) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL2673510 | 0.64 | ALDH1A1 (0.47) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL7127720 | 0.63 | ALDH1A1 (0.44) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL7877240 | 0.63 | ALDH1A1 (0.44) | USP2ALDH1A1LMNAALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |