Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660811 | 0.88 | LMNA (0.41) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL9579389 | 0.84 | LMNA (0.35) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL8218123 | 0.79 | LMNA (0.35) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL11636868 | 0.79 | PTPN1 (0.38) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL8218435 | 0.79 | LMNA (0.35) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL18458271 | 0.79 | LMNA (0.35) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL9191489 | 0.78 | LMNA (0.43) | PTPN1LMNACA1 | |
| SCHEMBL20009593 | 0.77 | LMNA (0.33) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL8215888 | 0.77 | PTPN1 (0.33) | PTPN1LMNAKDM1ACA1 | |
| SCHEMBL14216732 | 0.77 | PTPN1 (0.37) | PTPN1LMNAKDM1ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086784-A1 | Phosphonate analogs of HIV inhibitor compounds | GILEAD SCIENCES, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086784-A1 | Phosphonate analogs of HIV inhibitor compounds | PIK3CA, TYMP, ITPA | PTPN1 1475/4885LMNA 2426/4885KDM1A 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.