SCHEMBL20009850

SCHEMBL20009850

c1ccc(-c2ccc(Nc3ccc(-c4ccccc4-c4ccc(-n5c6ccccc6c6cc7ccccc7cc65)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
HDAC4 P56524 1/20 0.39
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTPN1 P18031 1/20 0.34
CDC25B P30305 1/20 0.34
MAPT P10636 2/20 0.33
EPHX2 P34913 1/20 0.32
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
ROCK1 Q13464 1/20 0.32
KMT2A Q03164 2/20 0.32
MAPK10 P53779 1/20 0.32
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009847 0.90 ALDH1A1 (0.36) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL20009756 0.89 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL24510263 0.88 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL22868942 0.87 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL21563410 0.87 ALDH1A1 (0.39) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL14029440 0.86 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL26541680 0.85 KDM4E (0.40) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL20009935 0.85 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL20812938 0.85 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL24296579 0.84 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573824-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2020-02-25 US disclosed
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-29 US disclosed
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, BMI1 L3MBTL1 1563/4885KDM4E 390/4885ATM 2315/4885
US-10573824-B2 Compound and organic electronic element comprising same OR10J3, ETV6, BMI1 L3MBTL1 1563/4885KDM4E 390/4885ATM 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.