SCHEMBL20009946

SCHEMBL20009946

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5cc(-c6ccncc6)nc(-c6ccccn6)c5)c4)c3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
LMNA P02545 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CCR1 P32246 2/20 0.45
CCR5 P51681 2/20 0.45
CCR8 P51685 2/20 0.45
TP53 P04637 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALPL P05186 1/20 0.45
HSP90AA1 P07900 1/20 0.45
ALPI P09923 1/20 0.45
ALPG P10696 1/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
GABRA1 P14867 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009953 0.97 GRM5 (0.44) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL20010037 0.97 GRM5 (0.44) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL20010141 0.97 GRM5 (0.44) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL20010270 0.96 GRM5 (0.45) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL20010280 0.96 GRM5 (0.45) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL24626606 0.92 MEN1 (0.45) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL24626820 0.92 KDM4E (0.51) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL20009950 0.92 ALDH1A1 (0.47) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL20010257 0.92 ALDH1A1 (0.47) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1
SCHEMBL18334134 0.92 KDM4E (0.53) KDM4ESMN1; SMN2LMNAL3MBTL1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320261-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-10-14 US disclosed
US-11081648-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-08-03 US disclosed
US-10468605-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2019-11-05 US disclosed
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 KDM4E 1692/4885SMN1; SMN2 3465/4885LMNA 3956/4885
US-20210320261-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 KDM4E 1821/4885SMN1; SMN2 3696/4885LMNA 4161/4885
US-10468605-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 KDM4E 1692/4885SMN1; SMN2 3465/4885LMNA 3956/4885
US-11081648-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 KDM4E 1692/4885SMN1; SMN2 3465/4885LMNA 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.