SCHEMBL20009981

SCHEMBL20009981

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc5[nH]c6ccc(-c7ccc(-c8ccccn8)cn7)cc6c5c4)n3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 4/20 0.45
CHEK1 O14757 1/20 0.42
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
GABRA1 P14867 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40
GABRA6 Q16445 2/20 0.40
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009966 0.99 HPGDS (0.46) HPGDSCHEK1RAB9ASMN1; SMN2GABRA1
SCHEMBL20010293 0.93 HPGDS (0.48) HPGDSCHEK1RAB9ASMN1; SMN2GABRA1
SCHEMBL23712243 0.91 HPGDS (0.49) HPGDSCHEK1RAB9ASMN1; SMN2GABRA1
SCHEMBL20010077 0.88 MKNK1 (0.45) HPGDSCHEK1RAB9ASMN1; SMN2GABRA1
SCHEMBL20010279 0.88 MKNK1 (0.45) HPGDSCHEK1RAB9ASMN1; SMN2GABRA1
SCHEMBL20009907 0.87 TLR8 (0.44) HPGDSCHEK1RAB9ASMN1; SMN2NPC1
SCHEMBL20010099 0.86 DHODH (0.43) HPGDSRAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL20009913 0.86 TLR8 (0.46) HPGDSCHEK1GABRA1GABRG2GABRB3
SCHEMBL20010190 0.86 CYP2A6 (0.46) HPGDSRAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL20010120 0.85 PIK3CD (0.42) HPGDSRAB9ASMN1; SMN2GABRA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320261-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-10-14 US disclosed
US-11081648-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-08-03 US disclosed
US-10468605-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2019-11-05 US disclosed
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 HPGDS 4477/4885CHEK1 4021/4885RAB9A 3547/4885
US-20210320261-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 HPGDS 4354/4885CHEK1 3716/4885RAB9A 3808/4885
US-10468605-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 HPGDS 4477/4885CHEK1 4021/4885RAB9A 3547/4885
US-11081648-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 HPGDS 4477/4885CHEK1 4021/4885RAB9A 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.