SCHEMBL20010128

SCHEMBL20010128

C=C1NC(=O)C(CC)=CN1C1O[C@H](CCP(=C)(C)C)[C@@H](O)[C@H]1O

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 7/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14946029 0.92 P2RY2 (0.35) P2RY2
SCHEMBL18118134 0.92 P2RY2 (0.35) P2RY2
SCHEMBL14928773 0.92 P2RY2 (0.35) P2RY2
SCHEMBL17463529 0.92 P2RY2 (0.35) P2RY2
SCHEMBL15249065 0.92 P2RY2 (0.35) P2RY2
SCHEMBL18118505 0.89 P2RY2 (0.36) P2RY2
SCHEMBL14928721 0.89 P2RY2 (0.36) P2RY2
SCHEMBL15249025 0.89 P2RY2 (0.36) P2RY2
SCHEMBL14945954 0.89 P2RY2 (0.36) P2RY2
SCHEMBL17463477 0.89 P2RY2 (0.36) P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086807-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE MODERNATX, INC. 2018-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086807-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE POLRMT, POLM, POLN P2RY2 3235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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