SCHEMBL14928721

SCHEMBL14928721

C=C1NC(=O)C(O)=CN1[C@@H]1O[C@H](CCP(=C)(C)C)[C@@H](O)[C@H]1O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 8/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15249025 1.00 P2RY2 (0.36) P2RY2
SCHEMBL18118505 1.00 P2RY2 (0.36) P2RY2
SCHEMBL14945954 1.00 P2RY2 (0.36) P2RY2
SCHEMBL17463477 1.00 P2RY2 (0.36) P2RY2
SCHEMBL20010128 0.89 P2RY2 (0.35) P2RY2
SCHEMBL15249018 0.89 P2RY2 (0.36) P2RY2
SCHEMBL17463479 0.89 P2RY2 (0.36) P2RY2
SCHEMBL18118099 0.89 P2RY2 (0.36) P2RY2
SCHEMBL14945957 0.89 P2RY2 (0.36) P2RY2
SCHEMBL14928661 0.89 P2RY2 (0.36) P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180170990-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS MODERNATX, INC. 2018-06-21 — — US disclosed
US-20180125937-A1 MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS MODERNATX, INC. (US) 2018-05-10 — — US disclosed
US-9878056-B2 Modified polynucleotides for the production of cosmetic proteins and peptides MODERNATX, INC. (US) 2018-01-30 — — US disclosed
US-20180002393-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF ONCOLOGY-RELATED PROTEINS AND PEPTIDES ARES CAPITAL CORPORATION, AS AGENT 2018-01-04 — — US disclosed
US-20170368200-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS ARES CAPITAL CORPORATION, AS AGENT 2017-12-28 — — US disclosed
US-20170348436-A1 IN VIVO PRODUCTION OF PROTEINS ARES CAPITAL CORPORATION, AS AGENT 2017-12-07 — — US disclosed
US-9828416-B2 Modified polynucleotides for the production of secreted proteins MODERNATX, INC. (US) 2017-11-28 — — US disclosed
US-9827332-B2 Modified polynucleotides for the production of proteins MODERNATX, INC. (US) 2017-11-28 — — US disclosed
US-9814760-B2 Modified polynucleotides for the production of biologics and proteins associated with human disease MODERNATX, INC. (US) 2017-11-14 — — US disclosed
US-9790531-B2 Enzymes and polymerases for the synthesis of RNA MODERNATX, INC. (US) 2017-10-17 — — US disclosed
US-20130253043-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF G-CSF modeRNA Therapeutics (US) 2013-09-26 — — US disclosed
US-20130245106-A1 METHOD OF PRODUCING A PROTEIN OF INTEREST modeRNA Therapeutics (US) 2013-09-19 — — US disclosed
US-20130244278-A1 FORMULATION AND DELIVERY OF PLGA MICROSPHERES modeRNA Therapeutics (US) 2013-09-19 — — US disclosed
US-20130245105-A1 DLIN-KC2-DMA LIPID NANOPARTICLE DELIVERY OF MODIFIED POLYNUCLEOTIDES modeRNA Therapeutics (US) 2013-09-19 — — US disclosed
US-20130244279-A1 FORMULATION AND DELIVERY OF PLGA MICROSPHERES modeRNA Therapeutics (US) 2013-09-19 — — US disclosed
US-20130236974-A1 METHOD FOR INCREASING THE PRODUCTION OF A PROTEIN OF INTEREST modeRNA Therapeutics (US) 2013-09-12 — — US disclosed
US-20130237593-A1 MULTI-SITE ADMINISTRATION modeRNA Therapeutics (US) 2013-09-12 — — US disclosed
US-20130237594-A1 SPLIT DOSE ADMINISTRATION modeRNA Therapeutics (US) 2013-09-12 — — US disclosed
US-20130156849-A1 MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS modeRNA Therapeutics (US) 2013-06-20 — — US disclosed
US-20130115272-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF modeRNA Therapeutics (US) 2013-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130237593-A1 MULTI-SITE ADMINISTRATION PHAX, IGF2BP1, NSUN2 P2RY2 3992/4885
US-20180170990-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS POLN, POLRMT, MSH2 P2RY2 3286/4885
US-20130236974-A1 METHOD FOR INCREASING THE PRODUCTION OF A PROTEIN OF INTEREST IGF2BP1, PHAX, IGF2BP2 P2RY2 4132/4885
US-20180125937-A1 MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS NSUN2, RNMT, NSUN3 P2RY2 1526/4885
US-20130237594-A1 SPLIT DOSE ADMINISTRATION IGF2BP1, IGF2BP2, NSUN2 P2RY2 3758/4885
US-20170368200-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS POLRMT, POLN, PHAX P2RY2 3852/4885
US-20130156849-A1 MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS NSUN2, RNMT, NSUN3 P2RY2 1526/4885
US-20170348436-A1 IN VIVO PRODUCTION OF PROTEINS MSH2, POLRMT, POLN P2RY2 3346/4885
US-20130245106-A1 METHOD OF PRODUCING A PROTEIN OF INTEREST IGF2BP1, PHAX, IGF2BP2 P2RY2 4142/4885
US-20180002393-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF ONCOLOGY-RELATED PROTEINS AND PEPTIDES MSH2, POLN, MSH6 P2RY2 3618/4885
US-20130245105-A1 DLIN-KC2-DMA LIPID NANOPARTICLE DELIVERY OF MODIFIED POLYNUCLEOTIDES KPNA2, NSUN2, PHAX P2RY2 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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