Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929114 | 0.81 | HPGD (0.36) | IMPDH2HPGDIMPDH1TAS1R3TAS1R1 | |
| SCHEMBL15044580 | 0.81 | HPGD (0.36) | IMPDH2HPGDIMPDH1TAS1R3TAS1R1 | |
| SCHEMBL20010244 | 0.81 | HPGD (0.39) | IMPDH2HPGDTAAR1IMPDH1TAS1R3 | |
| SCHEMBL20009991 | 0.78 | ADORA2A (0.42) | — | |
| SCHEMBL10072472 | 0.77 | IMPDH2 (0.34) | IMPDH2HPGDTAAR1IMPDH1STING1 | |
| SCHEMBL20010001 | 0.74 | HPGD (0.41) | IMPDH2HPGDTAAR1IMPDH1TAS1R3 | |
| SCHEMBL14928617 | 0.73 | HPGD (0.41) | IMPDH2HPGDIMPDH1TAS1R3TAS1R1 | |
| SCHEMBL15044555 | 0.73 | HPGD (0.41) | IMPDH2HPGDIMPDH1TAS1R3TAS1R1 | |
| SCHEMBL20009827 | 0.73 | HPGD (0.41) | IMPDH2HPGDTAAR1IMPDH1TAS1R3 | |
| SCHEMBL20010166 | 0.73 | HPGD (0.41) | IMPDH2HPGDTAAR1IMPDH1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086807-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE | MODERNATX, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086807-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE | POLRMT, POLM, POLN | IMPDH2 1300/4885HPGD 3640/4885TAAR1 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.