Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHI3L1 | P36222 | 1/20 | 0.44 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.44 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154169 | 0.87 | — | — | |
| SCHEMBL18255919 | 0.80 | CHI3L1 (0.40) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL12650362 | 0.80 | CHRNB2 (0.54) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL20320351 | 0.80 | CHRNB2 (0.54) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL18255915 | 0.79 | CHRNB2 (0.46) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL22629065 | 0.79 | CHRNB2 (0.46) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL20320356 | 0.78 | CHRNB2 (0.53) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL31227308 | 0.75 | SMYD3 (0.48) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| Hydrochloric Acid SCHEMBL31227128 | 0.74 | SMYD3 (0.49) | CHI3L1CHIT1CHI3L2CHIACHRNB2 | |
| SCHEMBL18255923 | 0.74 | CHRNB2 (0.45) | CHI3L1CHIT1CHI3L2CHIACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10278973-B2 | Hydroxyl purine compounds and use thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2019-05-07 | — | — | US | disclosed |
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3299371-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | PNP, PDE7A, PDE2A | CHI3L1 3937/4885CHIT1 3758/4885CHI3L2 3229/4885 |
| US-10278973-B2 | Hydroxyl purine compounds and use thereof | PNP, PDE7A, PDE2A | CHI3L1 3937/4885CHIT1 3758/4885CHI3L2 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.