Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21984235 | 0.82 | IDH1 (0.46) | ALDH1A1HPGDSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL1031878 | 0.81 | KMT2A (0.49) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL48879 | 0.81 | HPGD (0.58) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14127779 | 0.81 | HPGD (0.58) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL15854826 | 0.79 | RAPGEF4 (0.53) | HPGDSMN1; SMN2NPC1RAB9ANPSR1 | |
| SCHEMBL4278475 | 0.79 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNAPOLBRAPGEF4 | |
| SCHEMBL9274463 | 0.79 | HPGD (0.50) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2539187 | 0.78 | TRPV1 (0.58) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1033861 | 0.78 | HPGD (0.53) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1033939 | 0.77 | NPSR1 (0.58) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231680-B1 | LIGANDS FOR TRANSITION-METAL-CATALYZED CROSS-COUPLINGS, AND METHODS OF USE THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2018-03-28 | — | — | EP | disclosed |