Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.74 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.67 |
| ▸ | PNP | P00491 | 11/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743134 | 0.90 | TK1 (0.76) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL8196749 | 0.89 | TK1 (0.78) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL29286376 | 0.88 | TK1 (0.76) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL3793003 | 0.87 | TK1 (0.76) | TK1HPRT1PNP | |
| SCHEMBL9806969 | 0.87 | TK1 (0.71) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL27506929 | 0.86 | TK1 (0.74) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL6272731 | 0.86 | TK1 (0.74) | TK1HPRT1PNP | |
| SCHEMBL3836263 | 0.86 | TK1 (0.92) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL8522271 | 0.85 | TK1 (0.76) | TK1HPRT1PNP | |
| SCHEMBL571645 | 0.85 | TK1 (1.00) | TK1HPRT1PNPUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055071-A1 | PRODRUGS OF FLUORINATED ACYCLIC NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-03-29 | — | — | WO | disclosed |