Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607026 | 0.89 | HDAC3 (0.58) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL26023443 | 0.84 | CA1 (0.55) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL978502 | 0.84 | RAB9A (0.71) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6162284 | 0.84 | SMN1; SMN2 (0.79) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1745408 | 0.83 | FFAR1 (0.54) | PPARAALOX5PTGS1PTGS2MAOB | |
| SCHEMBL11350421 | 0.82 | RAB9A (0.82) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10236929 | 0.82 | RAB9A (0.82) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27395439 | 0.81 | RAB9A (0.68) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1746788 | 0.81 | FFAR1 (0.70) | PPARAALOX5PTGS1PTGS2POLB | |
| SCHEMBL9343582 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152204-B1 | CARBAMATE DERIVATIVES WHICH ARE BOTH PHOSPHODIESTERASE 4 (PDE4) ENZYME INHIBITORS AND MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-03-28 | — | — | EP | disclosed |