SCHEMBL978502

SCHEMBL978502

COC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 7/20 0.71
▸ MAPT P10636 4/20 0.71
▸ MAOB P27338 1/20 0.71
▸ SMN1; SMN2 Q16637 6/20 0.70
▸ NPC1 O15118 6/20 0.70
▸ MEN1 O00255 2/20 0.70
▸ KMT2A Q03164 2/20 0.70
▸ NR4A1 P22736 1/20 0.70
▸ NR4A2 P43354 1/20 0.70
▸ NR4A3 Q92570 1/20 0.70
▸ PARP10 Q53GL7 1/20 0.66
▸ SRD5A2 P31213 1/20 0.64
▸ LMNA P02545 1/20 0.63
▸ HPGD P15428 1/20 0.63
▸ HDAC3 O15379 1/20 0.61
▸ HDAC1 Q13547 1/20 0.61
▸ HDAC2 Q92769 1/20 0.61
▸ NCOR2 Q9Y618 1/20 0.61
▸ PLA2G4B P0C869 1/20 0.60
▸ POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341485 0.95 SMN1; SMN2 (0.65) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL9343582 0.95 SMN1; SMN2 (0.65) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL6162284 0.93 SMN1; SMN2 (0.79) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL11350421 0.91 RAB9A (0.82) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL10236929 0.91 RAB9A (0.82) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL1122731 0.91 SMN1; SMN2 (0.64) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL27395439 0.91 RAB9A (0.68) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL7776764 0.89 RAB9A (0.65) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL6255833 0.89 L3MBTL1 (0.62) RAB9AMAPTMAOBSMN1; SMN2NPC1
SCHEMBL898771 0.89 RXRA (0.77) RAB9AMAPTSMN1; SMN2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234918-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2023-07-27 — — US claimed
EP-4178942-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER Council Of Scientific & Industrial Research (IN) 2023-05-17 — — EP claimed
CN-115956066-A Automatic diazomethane generator, reactor and solid phase quenching agent 科学与工业研究委员会 2023-04-11 — — CN claimed
WO-2022044038-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-03-03 — — WO claimed
JP-59129194-A — — None — — JP disclosed
US-20250367143-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA PHARM INC (US) 2025-12-04 — — US disclosed
WO-2025244832-A1 NOVEL AMINOGUANIDINE DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF KONG'S PHARMACEUTICAL CO. (US) 2025-11-27 — — WO disclosed
EP-4543848-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA Pharmaceuticals Inc. (US) 2025-04-30 — — EP disclosed
CN-118307534-A LTA4H inhibitors and uses thereof 上海海雁医药科技有限公司 2024-07-09 — — CN disclosed
US-20240116897-A1 BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2024-04-11 — — US disclosed
WO-2023250059-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA PHARMACEUTICALS INC. (US) 2023-12-28 — — WO disclosed
EP-4269394-A1 BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT Korea Research Institute of Chemical Technology (KR) 2023-11-01 — — EP disclosed
EP-0312604-A1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1989-04-26 — — EP disclosed
US-4682193-A HEAT SENSITIVE, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 — — US disclosed
US-4672071-A Antihypertensive dihydropyridine compositions, optical isomers and intermediates SYNTEX (U.S.A.) INC. (US) 1987-06-09 — — US disclosed
EP-0199042-A1 Procainamide assay, tracers, immunogens and antibodies ABBOTT LABORATORIES (US) 1986-10-29 — — EP disclosed
EP-0191448-A2 Antihypertensive dihydropyridine derivatives SYNTEX (U.S.A.) INC. (US) 1986-08-20 — — EP disclosed
US-4595690-A Hypotensive agents SYNTEX (U.S.A.) INC. (US) 1986-06-17 — — US disclosed
JP-S59129194-A HEAT SENSITIVE RECORDING PAPER YOSHITOMI PHARMACEUT IND LTD 1984-07-25 — — JP disclosed
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367143-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 GPR88, GPR84, GPR68 RAB9A 795/4885MAPT 188/4885MAOB 1932/4885
US-20240116897-A1 BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT SIRT7, SIRT1, BRD7 RAB9A 2738/4885MAPT 957/4885MAOB 4450/4885
US-20230234918-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER FTO, MNAT1, ALKBH2 RAB9A 4756/4885MAPT 2101/4885MAOB 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback