Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24271760 | 1.00 | NAMPT (0.38) | NAMPTTSHRRAB9AHPGDNPC1 | |
| SCHEMBL20231659 | 0.89 | TSHR (0.43) | TSHRRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL12147609 | 0.86 | FAAH (0.41) | TSHRRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL30610964 | 0.86 | ALDH1A1 (0.43) | TSHRRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL22199469 | 0.85 | TSHR (0.43) | NAMPTTSHRHPGDMCL1L3MBTL1 | |
| SCHEMBL22841713 | 0.84 | TSHR (0.46) | TSHRHPGDSMN1; SMN2MCL1LMNA | |
| SCHEMBL21119034 | 0.84 | TSHR (0.46) | TSHRHPGDSMN1; SMN2MCL1LMNA | |
| SCHEMBL12081847 | 0.84 | TSHR (0.46) | TSHRHPGDSMN1; SMN2MCL1LMNA | |
| SCHEMBL2626750 | 0.84 | TSHR (0.46) | TSHRHPGDSMN1; SMN2MCL1LMNA | |
| SCHEMBL22199403 | 0.84 | GLP1R (0.41) | TSHRRAB9AHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086793-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086793-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | NAMPT 624/4885TSHR 1977/4885RAB9A 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.