Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 4/20 | 0.37 |
| ▸ | RXRB | P28702 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18277670 | 0.78 | RPA1 (0.46) | ALOX5CNR1CNR2ALDH1A1GAA | |
| SCHEMBL27795107 | 0.77 | ALDH1A1 (0.59) | ALOX5CNR1CNR2ALDH1A1GAA | |
| SCHEMBL19101969 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAAGRNSORT1KDM5A | |
| SCHEMBL27889993 | 0.77 | HTT (0.51) | ALOX5CNR1CNR2ALDH1A1GAA | |
| SCHEMBL3831066 | 0.74 | NOTUM (0.43) | ALOX5CNR1CNR2ALDH1A1GAA | |
| SCHEMBL15485403 | 0.74 | GRN (0.72) | ALDH1A1GAAGRNSORT1LMNA | |
| SCHEMBL17369126 | 0.73 | ALDH1A1 (0.59) | CNR1CNR2ALDH1A1GAAGRN | |
| SCHEMBL9468599 | 0.72 | KDM5A (0.43) | ALOX5CNR1CNR2ALDH1A1GRN | |
| SCHEMBL2934234 | 0.72 | KDM4E (0.47) | ALDH1A1GAAGRNSORT1LMNA | |
| SCHEMBL19388963 | 0.72 | PTGS1 (0.48) | ALOX5CNR1CNR2KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301288-B2 | Kinase inhibitors | TOPIVERT PHARMA LIMITED (GB) | 2019-05-28 | — | — | US | disclosed |
| US-20180086741-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086741-A1 | KINASE INHIBITORS | SYK, BTK, SRC | ALOX5 2655/4885CNR1 3571/4885CNR2 3280/4885 |
| US-10301288-B2 | Kinase inhibitors | SYK, BTK, SRC | ALOX5 2655/4885CNR1 3571/4885CNR2 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.