Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016891 | 0.91 | CYP11B1 (0.33) | DHODHCYP11B1PDK2TGFBR1BRD4 | |
| SCHEMBL20016800 | 0.91 | PIK3CA (0.37) | GRM5PIK3CACHEK1PDK2TGFBR1 | |
| SCHEMBL20016890 | 0.90 | PIK3CA (0.40) | FYNDHODHPIK3CACYP11B1CYP11B2 | |
| SCHEMBL20016879 | 0.90 | PIM1 (0.35) | CYP2A6GRM5FYNPIK3CAPIM1 | |
| SCHEMBL20016801 | 0.90 | PIK3CA (0.37) | CYP2A6FYNDHODHPIK3CAPIM1 | |
| SCHEMBL17132477 | 0.89 | TGFBR1 (0.35) | GRM5DHODHCYP11B1PDK2LMNA | |
| SCHEMBL16485096 | 0.89 | TGFBR1 (0.35) | GRM5DHODHCYP11B1PDK2LMNA | |
| SCHEMBL16484659 | 0.89 | CYP11B1 (0.40) | CYP2A6FYNDHODHPIK3CACYP11B1 | |
| SCHEMBL16485099 | 0.89 | CYP11B1 (0.40) | CYP2A6FYNDHODHPIK3CACYP11B1 | |
| SCHEMBL20016859 | 0.87 | FYN (0.35) | FYNPIK3CACYP11B1CYP11B2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9935273-B2 | Fluoranthene derivative, light-emitting device material containing same, and light-emitting device | TORAY INDUSTRIES, INC. (JP) | 2018-04-03 | — | — | US | disclosed |