Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17012236 | 0.93 | TGFBR1 (0.34) | CYP11B1TGFBR1HPGDS | |
| SCHEMBL20016795 | 0.91 | CYP2A6 (0.37) | CYP11B1TGFBR1BRD4DHODHPDK2 | |
| SCHEMBL20016800 | 0.91 | PIK3CA (0.37) | TGFBR1BRD4PRMT5PDK2 | |
| SCHEMBL16485096 | 0.91 | TGFBR1 (0.35) | CYP11B1TGFBR1BRD4DHODHPDK2 | |
| SCHEMBL17132477 | 0.91 | TGFBR1 (0.35) | CYP11B1TGFBR1BRD4DHODHPDK2 | |
| SCHEMBL16484448 | 0.89 | HPGDS (0.36) | CYP11B1TGFBR1HPGDSPDK2 | |
| SCHEMBL16485074 | 0.89 | CYP11B1 (0.35) | CYP11B1 | |
| SCHEMBL16484419 | 0.88 | PDK2 (0.36) | TGFBR1PRMT5DHODHPDK2 | |
| SCHEMBL16485097 | 0.88 | PRKDC (0.35) | TGFBR1DHODHPDK2 | |
| SCHEMBL20016878 | 0.86 | PIK3CA (0.39) | CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9935273-B2 | Fluoranthene derivative, light-emitting device material containing same, and light-emitting device | TORAY INDUSTRIES, INC. (JP) | 2018-04-03 | — | — | US | disclosed |