Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | MC5R | P33032 | 1/20 | 0.56 |
| ▸ | MC3R | P41968 | 1/20 | 0.56 |
| ▸ | MC1R | Q01726 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | AANAT | Q16613 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037221 | 0.77 | MC5R (0.73) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL17232881 | 0.77 | MC5R (0.83) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL3427633 | 0.77 | MC5R (0.64) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL12059084 | 0.76 | HTR2A (0.65) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL7970552 | 0.75 | MC5R (0.81) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL660463 | 0.75 | MC5R (0.66) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL29489675 | 0.75 | MC5R (0.66) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL9542634 | 0.74 | HTR2A (0.63) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL1972829 | 0.74 | HTR2A (1.00) | HTR2AMC5RMC3RMC1RKMT2A | |
| SCHEMBL30094716 | 0.73 | MC5R (0.68) | HTR2AMC5RMC3RMC1RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099684-B1 | HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION | NEUROPORE THERAPIES INC (US) | 2018-04-04 | — | — | EP | disclosed |