Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328105 | 0.97 | CNR1 (0.36) | CNR1DNM1SIGMAR1EPHX2 | |
| SCHEMBL28477740 | 0.93 | DNM1 (0.39) | DNM1SIGMAR1EPHX2 | |
| SCHEMBL19882101 | 0.90 | CNR1 (0.35) | CNR1 | |
| SCHEMBL2332115 | 0.90 | CNR1 (0.35) | CNR1 | |
| SCHEMBL28442815 | 0.86 | DNM1 (0.33) | DNM1EPHX2 | |
| SCHEMBL20018225 | 0.85 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL2621266 | 0.83 | CNR1 (0.35) | CNR1DNM1EPHX2 | |
| SCHEMBL246906 | 0.83 | CNR1 (0.35) | CNR1DNM1EPHX2 | |
| SCHEMBL14617143 | 0.83 | CNR1 (0.35) | CNR1DNM1EPHX2 | |
| SCHEMBL19414992 | 0.83 | CNR1 (0.35) | CNR1DNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2355851-B1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORP (CA) | 2018-04-04 | — | — | EP | disclosed |