Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 9/20 | 0.73 |
| ▸ | NR0B2 | Q15466 | 3/20 | 0.73 |
| ▸ | RARB | P10826 | 6/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | RARA | P10276 | 3/20 | 0.52 |
| ▸ | RARG | P13631 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29462722 | 0.94 | PTPN11 (0.66) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL20018663 | 0.87 | PTPN11 (0.56) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL20018689 | 0.87 | HDAC11 (0.59) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL2389152 | 0.86 | RARB (0.80) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL2389155 | 0.86 | RARB (0.80) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL2393228 | 0.85 | PTPN11 (0.71) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL1914215 | 0.85 | PTPN11 (1.00) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL2391204 | 0.85 | PTPN11 (0.77) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL2407028 | 0.85 | PTPN11 (0.77) | PTPN11NR0B2RARBHDAC11HDAC4 | |
| SCHEMBL2391213 | 0.85 | PTPN11 (0.77) | PTPN11NR0B2RARBHDAC11HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3301085-A1 | RETINOID DERIVATIVES WITH ANTITUMOR ACTIVITY | BIOGEM S.CA.R.L. (IT) | 2018-04-04 | — | — | EP | disclosed |