Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5561006 | 0.69 | SMN1; SMN2 (0.56) | ALDH1A1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL23411786 | 0.67 | KDM1A (0.47) | ALDH1A1KMT2AKDM1AMAOBRCOR1 | |
| SCHEMBL12624024 | 0.66 | GFER (0.56) | ALDH1A1KMT2AGFERKDM1AMAOB | |
| SCHEMBL17290928 | 0.64 | KMT2A (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12626285 | 0.63 | ALDH1A1 (0.56) | ALDH1A1KMT2AGFERKDM1AMAOB | |
| SCHEMBL12623932 | 0.63 | ALDH1A1 (0.56) | ALDH1A1GFERKDM1AMAOBRCOR1 | |
| SCHEMBL3847472 | 0.63 | ALDH1A1 (0.97) | ALDH1A1KMT2AGFERMAPTSMN1; SMN2 | |
| SCHEMBL16565682 | 0.63 | KMT2A (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL4412411 | 0.63 | KMT2A (0.74) | ALDH1A1KMT2ASMN1; SMN2MEN1CA12 | |
| SCHEMBL6406510 | 0.62 | MAPT (0.50) | ALDH1A1KMT2AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |