Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5561006 | 0.91 | SMN1; SMN2 (0.56) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL343359 | 0.87 | MAPT (0.52) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21244024 | 0.85 | LMNA (0.59) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6406201 | 0.79 | GSK3B (0.47) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2517845 | 0.78 | MAPT (0.55) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5249012 | 0.77 | SMN1; SMN2 (0.57) | MAPTHSD17B10SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL34672 | 0.76 | ALDH1A1 (0.66) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5563981 | 0.75 | ALDH1A1 (0.50) | MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4639473 | 0.74 | CA2 (0.59) | MAPTHSD17B10SMN1; SMN2ALDH1A1NPSR1 | |
| Lithium Ion SCHEMBL22638688 | 0.74 | CA1 (0.61) | MAPTHSD17B10SMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288376-A1 | Bicyclyl or heterobicyclylmethanesulfonylanimo-substituted N-hydroxyformamides | SMITHKLINE BEECHAM PLC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288376-A1 | Bicyclyl or heterobicyclylmethanesulfonylanimo-substituted N-hydroxyformamides | CD22, CD2, NEU3 | MAPT 4864/4885HSD17B10 960/4885SMN1; SMN2 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.