Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244670 | 0.87 | PSIP1 (0.47) | GRM2PSIP1MALT1CYP3A4DHODH | |
| SCHEMBL243265 | 0.87 | PSIP1 (0.47) | GRM2PSIP1MALT1CYP3A4DHODH | |
| SCHEMBL15182609 | 0.85 | CYP3A4 (0.40) | GRM2PSIP1MALT1CYP3A4NPC1 | |
| SCHEMBL3322579 | 0.85 | PSIP1 (0.37) | GRM2PSIP1MALT1CYP3A4NPC1 | |
| SCHEMBL20021129 | 0.82 | MCHR1 (0.32) | PSIP1CYP3A4 | |
| SCHEMBL247279 | 0.78 | PSIP1 (0.43) | GRM2PSIP1CYP3A4NPC1DHODH | |
| SCHEMBL246062 | 0.78 | PSIP1 (0.43) | GRM2PSIP1CYP3A4NPC1DHODH | |
| SCHEMBL20020744 | 0.78 | TLR7 (0.33) | PSIP1CYP3A4DHODH | |
| SCHEMBL243122 | 0.77 | PSIP1 (0.49) | GRM2PSIP1CYP3A4DHODH | |
| SCHEMBL243123 | 0.77 | PSIP1 (0.49) | GRM2PSIP1CYP3A4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |