SCHEMBL20020744 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TLR7	Q9NYK1	2/20	0.33

▸	TLR8	Q9NR97	1/20	0.33

▸	ALOX5AP	P20292	1/20	0.33

▸	PSIP1	O75475	1/20	0.32

▸	CYP3A4	P08684	1/20	0.31

▸	KMT2A	Q03164	1/20	0.30

▸	ATM	Q13315	1/20	0.30

▸	DHODH	Q02127	1/20	0.30

▸	NAMPT	P43490	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL241485	0.87	TLR7 (0.33)	TLR7TLR8ALOX5APPSIP1CYP3A4
SCHEMBL241486	0.87	TLR7 (0.33)	TLR7TLR8ALOX5APPSIP1CYP3A4
SCHEMBL20021129	0.86	MCHR1 (0.32)	PSIP1CYP3A4
SCHEMBL15182607	0.85	CYP3A4 (0.37)	TLR7TLR8ALOX5APPSIP1CYP3A4
SCHEMBL245419	0.85	PSIP1 (0.45)	TLR7TLR8PSIP1CYP3A4KMT2A
SCHEMBL20021172	0.82	MEN1 (0.36)	PSIP1KMT2A
SCHEMBL20020741	0.78	GRM2 (0.35)	PSIP1CYP3A4DHODH
SCHEMBL15182729	0.78	PSIP1 (0.37)	PSIP1CYP3A4KMT2AATMDHODH
SCHEMBL244789	0.77	CRHR1 (0.33)	ALOX5APPSIP1CYP3A4
SCHEMBL244790	0.77	CRHR1 (0.33)	ALOX5APPSIP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2588455-B1	2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS	GILEAD SCIENCES INC (US)	2018-04-04	—	—	EP	disclosed