Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23494092 | 0.90 | BLM (0.38) | BLMGABRR1GABRR2GABRR3LMNA | |
| SCHEMBL3626403 | 0.79 | BLM (0.50) | BLMGABRR1GABRR2GABRR3LMNA | |
| SCHEMBL3626405 | 0.79 | BLM (0.50) | BLMGABRR1GABRR2GABRR3LMNA | |
| SCHEMBL28883314 | 0.76 | NFKB1 (0.47) | PPARABLMLMNATSHRTDP1 | |
| SCHEMBL28912334 | 0.76 | NFKB1 (0.47) | PPARABLMLMNATSHRTDP1 | |
| SCHEMBL11765041 | 0.75 | ALDH1A1 (0.44) | LMNATDP1ALDH1A1 | |
| SCHEMBL11765044 | 0.75 | ALDH1A1 (0.44) | LMNATDP1ALDH1A1 | |
| Maleic Acid SCHEMBL17604468 | 0.75 | TSHR (0.53) | BLMGABRR1GABRR2GABRR3TSHR | |
| SCHEMBL11757239 | 0.75 | ALDH1A1 (0.36) | BLMLMNATDP1ALDH1A1 | |
| SCHEMBL4202881 | 0.75 | TSHR (0.39) | BLMGABRR1GABRR2GABRR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569273-B1 | NOVEL ANTIMICROBIAL COMPOUNDS AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2018-04-04 | — | — | EP | disclosed |