Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326729 | 0.89 | ACHE (0.47) | ACHEALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL20021083 | 0.79 | KMT2A (0.51) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL15182623 | 0.79 | ACHE (0.43) | ACHEALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL27910428 | 0.79 | ALDH1A1 (0.41) | ACHEALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL245545 | 0.78 | ACHE (0.42) | ACHEALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL27928087 | 0.73 | POLB (0.45) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11800152 | 0.69 | MAPT (0.60) | ACHEALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL20021050 | 0.69 | KMT2A (0.48) | ALDH1A1HSD17B10USP2HPGDTSHR | |
| SCHEMBL8691758 | 0.68 | CHRM1 (0.63) | ACHEALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL3303958 | 0.68 | KMT2A (0.49) | ALDH1A1HSD17B10USP2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |