Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251691 | 1.00 | PSIP1 (0.45) | PSIP1CYP3A4ROCK2PRKD3PRKCG | |
| SCHEMBL15182665 | 0.93 | PSIP1 (0.37) | PSIP1CYP3A4ROCK2PRKD3PRKCG | |
| SCHEMBL243700 | 0.91 | PSIP1 (0.50) | PSIP1CYP3A4 | |
| SCHEMBL10272175 | 0.89 | CYP3A4 (0.46) | PSIP1CYP3A4ROCK2PRKD3PRKCG | |
| SCHEMBL3304151 | 0.88 | PSIP1 (0.48) | PSIP1CYP3A4 | |
| SCHEMBL244852 | 0.88 | PSIP1 (0.46) | PSIP1CYP3A4 | |
| SCHEMBL20021109 | 0.88 | PSIP1 (0.46) | PSIP1CYP3A4 | |
| SCHEMBL246425 | 0.86 | PSIP1 (0.47) | PSIP1CYP3A4 | |
| SCHEMBL20021158 | 0.86 | PSIP1 (0.47) | PSIP1CYP3A4 | |
| SCHEMBL245429 | 0.86 | PSIP1 (0.45) | PSIP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |