Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62906 | 0.86 | KMT2A (0.48) | NPC1RAB9AAOC3KMT2ASMN1; SMN2 | |
| SCHEMBL25770001 | 0.85 | CNR2 (0.55) | NPC1RAB9AMAPTTP53LMNA | |
| Hydrochloric Acid SCHEMBL25228190 | 0.84 | KMT2A (0.51) | NPC1RAB9AAOC3KMT2ASMN1; SMN2 | |
| SCHEMBL15754349 | 0.84 | MEN1 (0.51) | AOC3LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4433479 | 0.82 | AOC3 (0.48) | NPC1RAB9AAOC3KMT2ASMN1; SMN2 | |
| SCHEMBL27169428 | 0.80 | MEN1 (0.48) | AOC3LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL24882086 | 0.80 | MEN1 (0.48) | AOC3KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL20021209 | 0.80 | CYP1A2 (0.53) | CYP1A2NPC1RAB9ALMNAPPARG | |
| SCHEMBL26117572 | 0.79 | ALDH1A1 (0.49) | AOC3MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL29906597 | 0.79 | HCRTR1 (0.43) | AOC3KMT2ASMN1; SMN2MEN1DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925745-B1 | CXCR7 ANTAGONISTS | CHEMOCENTRYX INC (US) | 2018-04-04 | — | — | EP | disclosed |