Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021304 | 0.93 | CYP19A1 (0.43) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL23024716 | 0.82 | CYP19A1 (0.46) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL20618592 | 0.81 | MAPT (0.43) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL21101055 | 0.79 | ALDH1A1 (0.47) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL20202149 | 0.79 | CHRNB4 (0.41) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL11783090 | 0.78 | NPC1 (0.42) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL22134628 | 0.77 | CYP19A1 (0.44) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL8344689 | 0.77 | CA2 (0.49) | CYP19A1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1208766 | 0.76 | NPC1 (0.55) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL14378361 | 0.76 | ALDH1A1 (0.39) | CYP19A1NPC1RAB9AAIMP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518744-B2 | Benzamide compound and preparation method, use, and pharmaceutical composition thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2022-12-06 | — | — | US | disclosed |
| US-10647678-B2 | Quinoline derivatives as inhibitors of heat shock factor 1 pathway activity | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2020-05-12 | — | — | US | disclosed |
| US-20180093955-A1 | QUINOLINE DERIVATIVES AS INHIBITORS OF HEAT SHOCK FACTOR 1 PATHWAY ACTIVITY | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-04-05 | — | — | US | disclosed |
| US-20180093955-A1 | QUINOLINE DERIVATIVES AS INHIBITORS OF HEAT SHOCK FACTOR 1 PATHWAY ACTIVITY | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093955-A1 | QUINOLINE DERIVATIVES AS INHIBITORS OF HEAT SHOCK FACTOR 1 PATHWAY ACTIVITY | HSF1, HSP90AB1, HSP90AB2P | CYP19A1 2468/4885NPC1 2250/4885RAB9A 1649/4885 |
| US-10647678-B2 | Quinoline derivatives as inhibitors of heat shock factor 1 pathway activity | HSF1, HSP90AB1, HSP90AB2P | CYP19A1 2468/4885NPC1 2250/4885RAB9A 1649/4885 |
| US-11518744-B2 | Benzamide compound and preparation method, use, and pharmaceutical composition thereof | JAK2, STAT3, STAT5A | CYP19A1 179/4885NPC1 3001/4885RAB9A 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.