Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077962 | 0.98 | ALDH1A1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL5617415 | 0.98 | ALDH1A1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL22085274 | 0.98 | ALDH1A1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL27727578 | 0.98 | ALDH1A1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL6078384 | 0.98 | ALDH1A1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL6079243 | 0.98 | ALDH1A1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL20031168 | 0.95 | NPC1 (0.41) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL23436811 | 0.83 | ALDH1A1 (0.42) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL20126492 | 0.83 | ALDH1A1 (0.42) | NPC1ALDH1A1L3MBTL1CRBNKMT2A | |
| SCHEMBL19157284 | 0.83 | ALDH1A1 (0.42) | NPC1ALDH1A1L3MBTL1CRBNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330248-A1 | ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11771775-B2 | Pyrrolobenzodiazepine-antibody conjugates | MEDIMMUNE LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
| US-20220008549-A1 | NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-01-13 | — | — | US | disclosed |
| US-20200345861-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | BLUE OWL OPPORTUNISTIC MASTER FUND I, L.P. (FORMERLY KNOWN AS OWL ROCK OPPORTUNISTIC MASTER FUND I, L.P.) | 2020-11-05 | — | — | US | disclosed |
| US-20180092985-A1 | SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES | MEDIMMUNE LIMITED (GB) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345861-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | CD79B, BCL6B, BCL6 | NPC1 3743/4885ALDH1A1 3769/4885L3MBTL1 959/4885 |
| US-20220008549-A1 | NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | STING1, CGAS, TLR9 | NPC1 1319/4885ALDH1A1 4336/4885L3MBTL1 3508/4885 |
| US-20230330248-A1 | ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE | STING1, CGAS, TLR9 | NPC1 1292/4885ALDH1A1 3436/4885L3MBTL1 3235/4885 |
| US-20180092985-A1 | SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES | SBDS, DCTD, DRD1 | NPC1 3503/4885ALDH1A1 442/4885L3MBTL1 1483/4885 |
| US-11771775-B2 | Pyrrolobenzodiazepine-antibody conjugates | CD79B, BCL6B, BCL6 | NPC1 3743/4885ALDH1A1 3769/4885L3MBTL1 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.