Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768476 | 0.95 | CTSS (0.43) | CTSS | |
| SCHEMBL18768477 | 0.95 | CTSS (0.43) | CTSS | |
| SCHEMBL7934082 | 0.95 | CTSS (0.43) | CTSS | |
| SCHEMBL14457549 | 0.95 | CTSS (0.43) | CTSS | |
| SCHEMBL12224897 | 0.94 | CTSS (0.36) | CTSS | |
| SCHEMBL20021632 | 0.93 | CTSS (0.44) | CTSS | |
| SCHEMBL7936003 | 0.90 | CTSS (0.42) | CTSS | |
| SCHEMBL18768644 | 0.90 | CTSS (0.42) | CTSS | |
| SCHEMBL13352032 | 0.89 | CTSS (0.42) | CTSS | |
| SCHEMBL11930627 | 0.88 | CTSS (0.42) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093943-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093943-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | CTRC, HAVCR2, HGFAC | CTSS 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.