⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950443 | 0.86 | NOS3 (0.33) | — | |
| SCHEMBL15481017 | 0.84 | — | — | |
| SCHEMBL22791637 | 0.78 | — | — | |
| SCHEMBL22791564 | 0.78 | — | — | |
| SCHEMBL9972014 | 0.77 | APLNR (0.30) | — | |
| SCHEMBL24966653 | 0.74 | APLNR (0.33) | — | |
| SCHEMBL179350 | 0.74 | NOS3 (0.41) | — | |
| SCHEMBL179362 | 0.74 | NPC1 (0.36) | — | |
| SCHEMBL22428868 | 0.74 | — | — | |
| SCHEMBL18494871 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365556-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20180093984-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2018-04-05 | — | — | US | disclosed |