Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025649 | 0.83 | ALDH1A1 (0.52) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL2893738 | 0.82 | ALDH1A1 (0.49) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1544338 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL6246323 | 0.79 | SMN1; SMN2 (0.65) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL26970988 | 0.79 | ALDH1A1 (0.59) | KMT2AALDH1A1TP53CYP3A4HPGD | |
| SCHEMBL2893486 | 0.78 | HDAC2 (0.48) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL6246318 | 0.78 | KMT2A (0.60) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1544493 | 0.74 | SMN1; SMN2 (0.49) | KMT2AALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL5752992 | 0.72 | HDAC2 (0.44) | KMT2AALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1544660 | 0.72 | TDP1 (0.51) | KMT2AALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | VANDERBILT UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | VANDERBILT UNIVERSITY | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | OR51E2, OR10J3, ORC3 | KMT2A 3451/4885ALDH1A1 2481/4885TP53 2705/4885 |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | OR51E2, OR10J3, ORC3 | KMT2A 3567/4885ALDH1A1 2668/4885TP53 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.