Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 16/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 16/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671268 | 0.89 | PDGFRB (0.46) | ALPLPDGFRBPDGFRA | |
| SCHEMBL23247161 | 0.76 | SNCA (0.53) | ALPLPDGFRBPDGFRADGAT1SNCA | |
| SCHEMBL16267992 | 0.76 | SNCA (0.50) | ALPLPDGFRBPDGFRADGAT1SNCA | |
| SCHEMBL23248010 | 0.75 | ALPL (0.41) | ALPLPDGFRBDGAT1SNCA | |
| SCHEMBL17419148 | 0.75 | ALPL (0.45) | ALPLPDGFRBDGAT1SNCA | |
| SCHEMBL20392825 | 0.73 | SNCA (0.50) | ALPLPDGFRBPDGFRADGAT1SNCA | |
| SCHEMBL3515122 | 0.73 | CSF1R (0.39) | ALPLPDGFRBDGAT1SNCA | |
| SCHEMBL29555798 | 0.73 | ALPL (0.46) | ALPLPDGFRBDGAT1SNCA | |
| SCHEMBL407919 | 0.73 | ALPL (0.46) | ALPLPDGFRBDGAT1SNCA | |
| SCHEMBL27890803 | 0.72 | PDGFRB (0.50) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828178-A1 | PYRIDINE SALTS AND PROCESS | Daiichi Sankyo Company, Limited (JP) | 2021-06-02 | — | — | EP | disclosed |
| EP-3519398-B1 | PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2021-02-24 | — | — | EP | disclosed |
| WO-2018060714-A1 | PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-04-05 | — | — | WO | disclosed |