Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 19/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 19/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021760 | 0.89 | ALPL (0.41) | PDGFRBPDGFRAALPL | |
| SCHEMBL23247161 | 0.80 | SNCA (0.53) | PDGFRBPDGFRAALPL | |
| SCHEMBL16267992 | 0.80 | SNCA (0.50) | PDGFRBPDGFRAALPL | |
| SCHEMBL3515122 | 0.77 | CSF1R (0.39) | PDGFRBALPL | |
| SCHEMBL29555798 | 0.77 | ALPL (0.46) | PDGFRBALPL | |
| SCHEMBL407919 | 0.77 | ALPL (0.46) | PDGFRBALPL | |
| SCHEMBL23247605 | 0.76 | ALPL (0.48) | PDGFRBALPL | |
| SCHEMBL19552677 | 0.76 | ALPL (0.38) | PDGFRBALPL | |
| SCHEMBL29718814 | 0.76 | ALPL (0.38) | PDGFRBALPL | |
| SCHEMBL67014 | 0.76 | PDGFRB (0.44) | PDGFRBALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163464-A1 | PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-03 | — | — | US | disclosed |
| US-10851092-B2 | Pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20200039974-A1 | PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039974-A1 | PYRIDINE COMPOUND | RET, ROS1, ABL1 | PDGFRB 735/4885PDGFRA 632/4885ALPL 4104/4885 |
| US-20210163464-A1 | PYRIDINE COMPOUND | RET, ABL1, ROS1 | PDGFRB 763/4885PDGFRA 655/4885ALPL 4154/4885 |
| US-10851092-B2 | Pyridine compound | RET, ROS1, ABL1 | PDGFRB 735/4885PDGFRA 632/4885ALPL 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.