SCHEMBL20022142

SCHEMBL20022142

Cc1cccc(-c2cc(-c3cc(F)cc(F)c3)cc(-c3cc(F)cc(F)c3)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.54
DHODH Q02127 1/20 0.45
GRM5 P41594 1/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
PTPN5 P54829 1/20 0.42
NR3C1 P04150 1/20 0.42
AR P10275 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ESR2 Q92731 1/20 0.41
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
NPY5R Q15761 1/20 0.40
ENPP3 O14638 1/20 0.40
IDO1 P14902 1/20 0.39
METAP2 P50579 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20022110 1.00 ACHE (0.54) ACHEDHODHGRM5RAB9ANPC1
SCHEMBL20022094 1.00 ACHE (0.54) ACHEDHODHGRM5RAB9ANPC1
SCHEMBL12225754 0.98 ACHE (0.56) ACHEDHODHGRM5RAB9ANPC1
SCHEMBL29674882 0.98 ACHE (0.56) ACHEDHODHGRM5RAB9ANPC1
SCHEMBL25014730 0.92 ACHE (0.61) ACHEDHODHGRM5RAB9ANPC1
SCHEMBL21279676 0.91 ACHE (0.60) ACHEDHODHGRM5RAB9ANPC1
SCHEMBL20022121 0.91 ACHE (0.67) ACHEDHODHRAB9ANPC1SMN1; SMN2
SCHEMBL20022107 0.89 ACHE (0.70) ACHERAB9ANPC1SMN1; SMN2TP53
SCHEMBL20022099 0.89 ACHE (0.70) ACHERAB9ANPC1SMN1; SMN2TP53
SCHEMBL6425293 0.86 ACHE (0.73) ACHERAB9ANPC1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-10-05 US disclosed
US-10689402-B2 Polycyclic aromatic compound and light emission layer-forming composition JNC CORPORATION (JP) 2020-06-23 US disclosed
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR ACHE 3716/4885DHODH 3800/4885GRM5 4107/4885
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR ACHE 3716/4885DHODH 3800/4885GRM5 4107/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR ACHE 3716/4885DHODH 3800/4885GRM5 4107/4885
US-10689402-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR ACHE 3716/4885DHODH 3800/4885GRM5 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.