Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21931883 | 0.91 | P2RX3 (0.54) | P2RX3P2RX2 | |
| SCHEMBL17823739 | 0.85 | P2RX3 (0.54) | P2RX3P2RX2 | |
| SCHEMBL17824060 | 0.85 | P2RX3 (0.69) | P2RX3P2RX2 | |
| SCHEMBL19969493 | 0.83 | P2RX3 (0.82) | P2RX3P2RX2 | |
| SCHEMBL17824039 | 0.81 | P2RX3 (0.71) | P2RX3P2RX2 | |
| SCHEMBL17824116 | 0.80 | P2RX3 (0.53) | P2RX3P2RX2 | |
| SCHEMBL17823976 | 0.78 | P2RX3 (0.72) | P2RX3P2RX2 | |
| SCHEMBL17823669 | 0.78 | P2RX3 (0.72) | P2RX3P2RX2 | |
| SCHEMBL19950547 | 0.77 | P2RX3 (0.54) | P2RX3P2RX2 | |
| SCHEMBL30277293 | 0.77 | P2RX3 (0.54) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053411-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-23 | — | — | US | disclosed |
| US-11142523-B2 | 1,3-thiazol-2-yl substituted benzamides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-12 | — | — | US | disclosed |
| US-20200131169-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-30 | — | — | US | disclosed |
| US-10202369-B2 | 1,3-thiazol-2-yl substituted benzamides | BAYER AKTIENGESELLSCHAFT (DE) | 2019-02-12 | — | — | US | disclosed |
| US-20180093980-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | EVOTEC AG (DE) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093980-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | NAT1, HNMT, PMP22 | P2RX3 578/4885P2RX2 541/4885 |
| US-20230053411-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | NAT1, HNMT, PMP22 | P2RX3 578/4885P2RX2 541/4885 |
| US-10202369-B2 | 1,3-thiazol-2-yl substituted benzamides | NAT1, HNMT, PMP22 | P2RX3 578/4885P2RX2 541/4885 |
| US-11142523-B2 | 1,3-thiazol-2-yl substituted benzamides | NAT1, HNMT, PMP22 | P2RX3 578/4885P2RX2 541/4885 |
| US-20200131169-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | NAT1, HNMT, PMP22 | P2RX3 578/4885P2RX2 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.