Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 4/20 | 0.52 |
| ▸ | MET | P08581 | 13/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 5/20 | 0.51 |
| ▸ | KDR | P35968 | 5/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022552 | 0.95 | PTK2B (0.57) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL20026834 | 0.90 | MET (0.54) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL18163505 | 0.85 | MET (0.57) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL20022484 | 0.84 | PTK2B (0.57) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL20022559 | 0.83 | MET (0.55) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL20022555 | 0.82 | MET (0.62) | METAXLSYKCSF1R | |
| SCHEMBL20022509 | 0.82 | PTK2B (0.57) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL20022498 | 0.82 | MET (0.55) | PTK2BMETAXLIGF1RKDR | |
| SCHEMBL20022562 | 0.81 | MET (0.62) | METAXLSYKCSF1R | |
| SCHEMBL20022546 | 0.81 | MET (0.55) | METAXLSYKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | TYRO3, MERTK, AXL | PTK2B 28/4885MET 5/4885AXL 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.