Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060334 | 0.90 | KMT2A (0.58) | APPALDH1A1KMT2AFFAR4PLAAT3 | |
| SCHEMBL7059127 | 0.80 | PLAAT3 (0.61) | ALDH1A1KMT2AFFAR4PLAAT3PLAAT5 | |
| SCHEMBL7060138 | 0.80 | PLAAT3 (0.58) | HPGDSMN1; SMN2ALDH1A1KMT2AFFAR4 | |
| SCHEMBL7061713 | 0.80 | PLAAT3 (0.57) | ALDH1A1KMT2AFFAR4PLAAT3PLAAT5 | |
| SCHEMBL1207379 | 0.80 | FFAR1 (0.57) | HPGDKMT2AFFAR4OPRD1FFAR1 | |
| SCHEMBL7060700 | 0.79 | TDP1 (0.56) | SMN1; SMN2ALDH1A1KMT2AFFAR4PLAAT5 | |
| SCHEMBL7061701 | 0.79 | ABCB1 (0.50) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7058700 | 0.79 | MTNR1A (0.52) | KMT2AMEN1L3MBTL1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL1375864 | 0.78 | FFAR1 (0.56) | HPGDSMN1; SMN2ALDH1A1KMT2AFFAR4 | |
| SCHEMBL7059739 | 0.78 | CYP1A2 (0.57) | FFAR4FFAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | GENZYME CORPORATION | 2018-04-05 | — | — | US | disclosed |
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | GENZYME CORPORATION | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | ASAH2, GBA1, GAA | APP 808/4885HPGD 1055/4885SMN1; SMN2 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.