Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306818 | 0.79 | TSHR (0.40) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL8233153 | 0.77 | TAAR1 (0.46) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL8431393 | 0.77 | CYP1A2 (0.38) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL19588486 | 0.77 | PNMT (0.38) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL3915756 | 0.76 | TAAR1 (0.45) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL18782487 | 0.76 | SLC6A2 (0.37) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11403685 | 0.73 | CYP1A2 (0.41) | IDO1PNMTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17755386 | 0.72 | IDH1 (0.37) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL15786471 | 0.72 | MEN1 (0.39) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL6303923 | 0.72 | TSHR (0.35) | IDO1PNMTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604520-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20180093984-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604520-B2 | N-acyl amino acid compounds and methods of use | ITGA1, ITGB1, ITGAL | IDO1 2209/4885PNMT 3064/4885CYP1A2 3869/4885 |
| US-20180093984-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | ITGA1, ITGB1, ITGAL | IDO1 2209/4885PNMT 3064/4885CYP1A2 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.