Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028942 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MIFNOS2LTA4HNOS3 | |
| SCHEMBL4073891 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MIFNOS2LTA4HNOS3 | |
| SCHEMBL29956618 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MIFNOS2LTA4HNOS3 | |
| SCHEMBL7510293 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MIFLTA4HESR1ESR2 | |
| SCHEMBL2557114 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MIFNOS2LTA4HNOS3 | |
| SCHEMBL2554121 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MIFNOS2LTA4HNOS3 | |
| SCHEMBL8295626 | 0.82 | SLC7A5 (0.49) | ALDH1A1NOS2LTA4HNOS3NOS1 | |
| SCHEMBL18059440 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MIFLTA4HESR1ESR2 | |
| SCHEMBL20739890 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MIFLTA4HESR1ESR2 | |
| SCHEMBL12313856 | 0.82 | MIF (0.53) | ALDH1A1MIFNOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604520-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20180093984-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604520-B2 | N-acyl amino acid compounds and methods of use | ITGA1, ITGB1, ITGAL | ALDH1A1 524/4885TAS1R3 1749/4885TAS1R1 785/4885 |
| US-20180093984-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | ITGA1, ITGB1, ITGAL | ALDH1A1 524/4885TAS1R3 1749/4885TAS1R1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.