Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 14/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025020 | 0.92 | MGLL (0.34) | CHRM2CHRM3MGLLEIF2AK4PIK3CA | |
| SCHEMBL20024916 | 0.89 | CHRM2 (0.36) | CHRM2CHRM3MGLLEIF2AK4P4HB | |
| SCHEMBL20025496 | 0.84 | CHRM2 (0.35) | CHRM2CHRM3MGLLPIK3CDPIK3CA | |
| SCHEMBL20025373 | 0.81 | CHRM2 (0.32) | CHRM2CHRM3FFAR1 | |
| SCHEMBL20025377 | 0.81 | CHRM2 (0.38) | CHRM2CHRM3MGLLP4HBFFAR1 | |
| SCHEMBL20025011 | 0.80 | CHRM2 (0.39) | CHRM2CHRM3MGLLP4HBFFAR1 | |
| SCHEMBL28688585 | 0.79 | CHRM2 (0.38) | CHRM2CHRM3MGLLFFAR1METTL3 | |
| SCHEMBL1246088 | 0.79 | CHRM2 (0.60) | CHRM2CHRM3 | |
| SCHEMBL12913087 | 0.77 | CHRM2 (0.39) | CHRM2CHRM3 | |
| SCHEMBL20025382 | 0.77 | CHRM2 (0.37) | CHRM2CHRM3MGLLFFAR1METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059537-A1 | DIAZASPIRO[5.5]UNDECANE DERIVATIVE AND USE THEREOF | 四川海思科制药有限公司 | 2018-04-05 | — | — | WO | disclosed |