Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025377 | 0.92 | CHRM2 (0.38) | CHRM2CHRM3TBK1METTL3P4HB | |
| SCHEMBL20025011 | 0.91 | CHRM2 (0.39) | CHRM2CHRM3METTL3P4HBMGLL | |
| SCHEMBL28688585 | 0.90 | CHRM2 (0.38) | CHRM2CHRM3METTL3MGLLFFAR1 | |
| SCHEMBL20025375 | 0.89 | CHRM2 (0.36) | CHRM2CHRM3METTL3P4HBMGLL | |
| SCHEMBL20025020 | 0.89 | MGLL (0.34) | CHRM2CHRM3TBK1METTL3MGLL | |
| SCHEMBL20025382 | 0.87 | CHRM2 (0.37) | CHRM2CHRM3METTL3MGLLFFAR1 | |
| SCHEMBL20025304 | 0.85 | SIGMAR1 (0.41) | DRD2DRD3 | |
| SCHEMBL20025288 | 0.84 | SIGMAR1 (0.37) | CHRM2CHRM3METTL3FFAR1DRD3 | |
| SCHEMBL20025335 | 0.84 | CHRM2 (0.35) | CHRM2CHRM3METTL3MGLLFFAR1 | |
| SCHEMBL20025290 | 0.83 | SIGMAR1 (0.32) | CHRM2CHRM3METTL3MGLLEIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059537-A1 | DIAZASPIRO[5.5]UNDECANE DERIVATIVE AND USE THEREOF | 四川海思科制药有限公司 | 2018-04-05 | — | — | WO | disclosed |