Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025378 | 0.86 | EIF2AK4 (0.47) | GPR119MGLLEIF2AK4 | |
| SCHEMBL20025065 | 0.85 | GPR119 (0.59) | GPR119MGLLEIF2AK4 | |
| SCHEMBL20025248 | 0.85 | EIF2AK4 (0.48) | GPR119MGLLEIF2AK4 | |
| SCHEMBL20025262 | 0.84 | EIF2AK4 (0.46) | GPR119HSD17B10ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL20025085 | 0.84 | GPR119 (0.55) | GPR119HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL22941868 | 0.84 | HSD17B10 (0.69) | GPR119HSD17B10ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL20025300 | 0.83 | EIF2AK4 (0.45) | GPR119MGLLEIF2AK4 | |
| SCHEMBL20024996 | 0.83 | EIF2AK4 (0.55) | GPR119ALDH1A1MGLLEIF2AK4 | |
| SCHEMBL20025388 | 0.83 | EIF2AK4 (0.47) | GPR119ALDH1A1MAPK1MGLLEIF2AK4 | |
| SCHEMBL20025234 | 0.82 | EIF2AK4 (0.45) | GPR119EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059537-A1 | DIAZASPIRO[5.5]UNDECANE DERIVATIVE AND USE THEREOF | 四川海思科制药有限公司 | 2018-04-05 | — | — | WO | disclosed |