Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025378 | 0.88 | EIF2AK4 (0.47) | EIF2AK4NAMPTGPR119LRRK2MGLL | |
| SCHEMBL20025248 | 0.87 | EIF2AK4 (0.48) | EIF2AK4HRH3NAMPTGPR119MGLL | |
| SCHEMBL20025234 | 0.87 | EIF2AK4 (0.45) | EIF2AK4HRH3NAMPTGPR119 | |
| SCHEMBL20025388 | 0.86 | EIF2AK4 (0.47) | EIF2AK4NAMPTGPR119LRRK2ALDH1A1 | |
| SCHEMBL20025300 | 0.86 | EIF2AK4 (0.45) | EIF2AK4NAMPTGPR119MGLLPIK3CA | |
| SCHEMBL20024996 | 0.86 | EIF2AK4 (0.55) | EIF2AK4HRH3NAMPTGPR119ALDH1A1 | |
| SCHEMBL20025418 | 0.84 | ALDH1A1 (0.46) | EIF2AK4NAMPTGPR119LRRK2ALDH1A1 | |
| SCHEMBL20025475 | 0.84 | GPR119 (0.59) | EIF2AK4GPR119ALDH1A1CYP2D6HSD17B10 | |
| SCHEMBL20025389 | 0.83 | EIF2AK4 (0.45) | EIF2AK4NAMPTGPR119LRRK2MGLL | |
| SCHEMBL20025065 | 0.82 | GPR119 (0.59) | EIF2AK4NAMPTGPR119MGLLPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059537-A1 | DIAZASPIRO[5.5]UNDECANE DERIVATIVE AND USE THEREOF | 四川海思科制药有限公司 | 2018-04-05 | — | — | WO | disclosed |