SCHEMBL20025516

SCHEMBL20025516

Cc1c(C)n(-c2ccccc2)c2ccc3ccccc3c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ HPGD P15428 3/20 0.44
▸ ATM Q13315 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ CYP3A4 P08684 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ CASP7 P55210 1/20 0.44
▸ HIF1A Q16665 1/20 0.44
▸ KDM4E B2RXH2 3/20 0.41
▸ EGFR P00533 1/20 0.41
▸ CYP1A2 P05177 2/20 0.40
▸ CYP2A6 P11509 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ GAA P10253 1/20 0.39
▸ GFER P55789 1/20 0.39
▸ HTT P42858 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20025359 0.85 MAPK1 (0.38) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL13086954 0.82 ATM (0.56) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL31756961 0.81 HPGD (0.48) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL1920722 0.81 HPGD (0.48) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL1755427 0.77 L3MBTL1 (0.61) L3MBTL1ATMTSHRMAPK1HSD17B10
SCHEMBL30181013 0.77 L3MBTL1 (0.61) L3MBTL1ATMTSHRMAPK1HSD17B10
SCHEMBL23348123 0.76 L3MBTL1 (0.42) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL16905752 0.76 ALDH1A1 (0.43) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL257004 0.76 L3MBTL1 (0.46) L3MBTL1HPGDATMTSHRMAPK1
SCHEMBL20730411 0.76 L3MBTL1 (0.43) L3MBTL1HPGDATMTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180095363-A1 PHOTOACID-GENERATING COMPOUND AND ASSOCIATED POLYMER, PHOTORESIST COMPOSITION, AND METHOD OF FORMING A PHOTORESIST RELIEF IMAGE U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180095363-A1 PHOTOACID-GENERATING COMPOUND AND ASSOCIATED POLYMER, PHOTORESIST COMPOSITION, AND METHOD OF FORMING A PHOTORESIST RELIEF IMAGE PARN, ZYX, LBR L3MBTL1 1797/4885HPGD 2302/4885ATM 1652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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