Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.44 |
| ▸ | TUBB | P07437 | 5/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636412 | 1.00 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16010332 | 0.84 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24175669 | 0.79 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5687768 | 0.72 | TUBB1 (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5689307 | 0.72 | TUBB1 (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5687761 | 0.72 | TUBB1 (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10372067 | 0.71 | SLC6A2 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3480388 | 0.71 | MAPT (0.34) | MAPTTSHR | |
| SCHEMBL5758557 | 0.69 | MAPT (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4803640 | 0.69 | SLC6A2 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536672-A1 | STING AGONIST COMPOUNDS | Sutro Biopharma, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239675-A1 | STING AGONIST COMPOUNDS | SUTRO BIOPHARMA, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023239675-A1 | STING AGONIST COMPOUNDS | SUTRO BIOPHARMA, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |
| WO-2022002077-A1 | ARYL AROMATIC HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2022-01-06 | — | — | WO | disclosed |
| US-10793557-B2 | Sting agonist compounds | MERCK SHARP & DOHME CORP. (US) | 2020-10-06 | — | — | US | disclosed |
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-04 | — | — | US | disclosed |
| US-10703738-B2 | Benzo[b]thiophene compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190337917-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-11-07 | — | — | US | disclosed |
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |
| US-20190300513-A1 | STING AGONIST COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-10-03 | — | — | US | disclosed |
| US-10414747-B2 | Benzo[b]thiophene compounds as sting agonists | MERCK SHARP & DOHME CORP. (US) | 2019-09-17 | — | — | US | disclosed |
| WO-2018067423-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2018-04-12 | — | — | WO | disclosed |
| US-20180093964-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300513-A1 | STING AGONIST COMPOUNDS | STING1, CGAS, IRF3 | TUBB4A 3502/4885TUBB 3958/4885TUBA3C 4613/4885 |
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | STING1, IRF3, CGAS | TUBB4A 3145/4885TUBB 3006/4885TUBA3C 4019/4885 |
| US-20180093964-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | STING1, IRF3, CGAS | TUBB4A 3145/4885TUBB 3006/4885TUBA3C 4019/4885 |
| US-10793557-B2 | Sting agonist compounds | STING1, CGAS, IRF3 | TUBB4A 3502/4885TUBB 3958/4885TUBA3C 4613/4885 |
| US-10414747-B2 | Benzo[b]thiophene compounds as sting agonists | STING1, IRF3, CGAS | TUBB4A 3145/4885TUBB 3006/4885TUBA3C 4019/4885 |
| US-20190337917-A1 | BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS | STING1, IRF3, CGAS | TUBB4A 3145/4885TUBB 3006/4885TUBA3C 4019/4885 |
| US-10703738-B2 | Benzo[b]thiophene compounds as STING agonists | STING1, IRF3, CGAS | TUBB4A 3145/4885TUBB 3006/4885TUBA3C 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.