Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 4/20 | 0.30 |
| ▸ | MC5R | P33032 | 4/20 | 0.30 |
| ▸ | MC3R | P41968 | 4/20 | 0.30 |
| ▸ | MC1R | Q01726 | 4/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532336 | 1.00 | PRCP (0.32) | PRCPPYGLITGA4ITGB7MAPK11 | |
| SCHEMBL17492920 | 0.95 | PYGL (0.32) | PRCPPYGL | |
| SCHEMBL17459556 | 0.95 | PYGL (0.32) | PRCPPYGL | |
| SCHEMBL22167241 | 0.95 | PYGL (0.32) | PRCPPYGL | |
| SCHEMBL17532347 | 0.94 | PYGL (0.31) | PRCPPYGLMC4RMC5RMC3R | |
| SCHEMBL22167196 | 0.94 | PYGL (0.31) | PYGL | |
| SCHEMBL21878967 | 0.94 | F2 (0.33) | PYGL | |
| SCHEMBL21878969 | 0.94 | F2 (0.33) | PYGL | |
| SCHEMBL17492915 | 0.94 | F2 (0.33) | PYGL | |
| SCHEMBL17492914 | 0.94 | F2 (0.33) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519407-B1 | DIMETHYLAMINOETHANOL SALT OF A GLP-1 RECEPTOR MODULATOR | RECEPTOS LLC (US) | 2021-09-22 | — | — | EP | disclosed |
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |
| WO-2018064476-A1 | DIMETHYLAMINOETHANOL SALT OF A GLP-1 RECEPTOR MODULATOR | CELGENE INTERNATIONAL II SARL (CH) | 2018-04-05 | — | — | WO | disclosed |