Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alosetron SCHEMBL148316 | 0.88 | HTR2A (0.74) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| Alosetron SCHEMBL311317 | 0.87 | CASP6 (0.74) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| Alosetron SCHEMBL7371660 | 0.87 | CASP6 (0.74) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| SCHEMBL702 | 0.86 | KCNH2 (0.78) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| SCHEMBL20022665 | 0.85 | HTR2A (0.56) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| SCHEMBL3321223 | 0.82 | KCNH2 (0.54) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| Alosetron SCHEMBL2229995 | 0.81 | KCNH2 (0.65) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| SCHEMBL766 | 0.80 | KCNH2 (0.75) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| Fumaric Acid SCHEMBL582 | 0.80 | KCNH2 (0.68) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C | |
| Maleic Acid SCHEMBL581 | 0.80 | KCNH2 (0.68) | KCNH2ADRA1ACYP1A2CYP3A4ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094015-A1 | ENZYME-DIRECTED IMMUNOSTIMULANT AND USES THEREOF CROSS-REFERENCE TO RELATED APPLICATION(S) | WASHINGTON STATE UNIVERSITY | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094015-A1 | ENZYME-DIRECTED IMMUNOSTIMULANT AND USES THEREOF CROSS-REFERENCE TO RELATED APPLICATION(S) | ACHE, GUSB, ENGASE | KCNH2 4788/4885ADRA1A 3256/4885CYP1A2 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.